Product Identification
【Product Name】4'-Hydroxy-3'-methoxyacetophenone 香草酮
【Synonyms】
1-(4-Hydroxy-3-methoxyphenyl)ethanone
4-Acetyl-2-methoxyphenol
4-Acetylguaiacol
4'-Hydroxy-3'-methoxyacetophenone
Acetoguaiacone
Acetovanillone
【CAS】498-02-2
【Formula】C9H10O3
【Molecular Weight】166.18
【EINECS】207-854-5
【RTECS】AM8800000
【RTECS Class】Drug; Mutagen
【Merck】13,746
【Beilstein/Gmelin】637373
【Beilstein Reference】4-08-00-01814
Physical and Chemical Properties
【Appearance】Light yellow to yellow solid. Faint vanilla odor.
【Solubility in water】Slightly soluble
【Melting Point】115
【Boiling Point】295
【Vapor Pressure】0.0008 (25 C)
【pKa/pKb】8.17 (pKa)
【Partition Coefficient】1.38
【Heat Of Vaporization】55.9 kJ/mol
【Usage】A plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis.
First Aid Measures
【Ingestion】Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Hazards Identification
【Ingestion】The toxicological properties of this substance have not been fully investigated.
【Inhalation】The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 36/37/38
【EC Safety Phrase】S 26 36
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Fire Fighting Measures
【Flash Point】126
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability and Reactivity
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidants.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Transport Information
【HS Code】2914 50 00