Product Identification
【Product Name】1-(4-Chlorophenyl)ethanone
【Synonyms】4-Chloroacetophenone ；对氯苯乙酮
【CAS】99-91-2
【Formula】C8H7ClO
【Molecular Weight】154.6
【EINECS】202-800-7
【RTECS】KM5600000
【RTECS Class】Human Data
【Merck】13,2133
【Beilstein/Gmelin】386014
【Beilstein Reference】4-07-00-00639
【EC Class】irritant

Physical and Chemical Properties
【Appearance】Liquid.
【Solubility in water】Insoluble
【Melting Point】18-20℃
【Boiling Point】232℃
【Vapor Pressure】0.04 (25℃)
【Density】1.1952 g/cm3 (20℃)
【Partition Coefficient】2.32
【Heat Of Vaporization】47.5 kJ/mol
【Usage】Chemical intermediate for pharmaceuticals.
【Vapor Density】5.3
【Refractive Index】1.5511 (20℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
【Handling】Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.

Hazards Identification
【Inhalation】Causes respiratory tract irritation. May cause burns to the respiratory tract.
【Skin】Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause contact dermatitis.
【Eyes】Causes eye irritation. Lachrymator.
【Ingestion】Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause burns to the gastrointestinal tract.
【Hazards】When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】R 20/22 36/38
【EC Safety Phrase】S 26 36/37/39
【UN (DOT)】1697

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate clothing to prevent skin exposure.
【Respirators】Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Exposure Effects】Prolonged or repeated skin contact may cause dermatitis. May cause allergic skin reaction in some individuals.
【Poison Class】3

Fire Fighting Measures
【Flash Point】107℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
【Fire Potential】Combustible material: may burn but does not ignite ily.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity
【Disposal Code】9
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】1697
【Hazard Class】6.1
【Packing Group】II
【HS Code】2914 70 90