Product Identification
【Product Name】2-Propynoic acid methyl ester
【Synonyms】Methyl propargylate；丙炔酸甲酯
【CAS】922-67-8
【Formula】C4H4O2
【Molecular Weight】84.07
【EINECS】213-083-5
【RTECS】UE0050000
【RTECS Class】Other
【Beilstein/Gmelin】605462
【Beilstein Reference】4-02-00-01688
【EC Class】highly flammable, irritant

Physical and Chemical Properties
【Appearance】Clear, colorless liquid.
【Solubility in water】Soluble
【Boiling Point】105℃
【Vapor Pressure】32 (25℃)
【Density】1.196 g/cm3 (20℃)
【Partition Coefficient】.89
【Heat Of Vaporization】34.3 kJ/mol
【Vapor Density】2.9
【Refractive Index】1.4085 (19.1℃)

First Aid Measures
【Ingestion】Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage
【Storage】Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
【Handling】Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or flames.

Hazards Identification
【Inhalation】Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. May cause burning sensation in the chest.
【Skin】Causes skin irritation. May cause cyanosis of the extremities.
【Eyes】Causes eye irritation. Lachrymator. May cause chemical conjunctivitis and corneal damage.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
【Hazards】Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will sp along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
【EC Risk Phrase】R 11 36/37/38
【EC Safety Phrase】S 16 26 36/37/39
【UN (DOT)】1993

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】Prolonged or repeated skin contact may cause dermatitis. Effects may be delayed.

Fire Fighting Measures
【Flash Point】10℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be sp by the use of water. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire.
【Fire Potential】HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity
【Incompatibilities】Oxidizing agents, acids, bases.
【Stability】Stable under normal temperatures and pressures.
【Decomposition】Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】1993
【Hazard Class】3
【Packing Group】I; II; III
【HS Code】2916 19 80