Product Identification
【Product Name】4-Methylbenzenesulfonic acid ethyl ester
【Synonyms】Ethyl tosylate；对甲苯磺酸乙酯
【CAS】80-40-0
【Formula】C9H12O3S
【Molecular Weight】200.26
【EINECS】201-276-7
【RTECS】XT6825000
【RTECS Class】Tumorigen; Mutagen
【Merck】13,3889
【Beilstein/Gmelin】611213
【Beilstein Reference】4-11-00-00248

Physical and Chemical Properties
【Appearance】White crystals.
【Solubility in water】Insoluble
【Melting Point】30~32℃
【Boiling Point】158℃
【Vapor Pressure】.45
【Density】1.166 g/cm3 (16℃)
【Usage】Plasticizer for cellulose acetate, ethylating agent.
【Vapor Density】8.09
【Refractive Index】1.5131 (20℃)

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage
【Storage】Refrigerator (approx 4 C). Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use and store under nitrogen. Use only in a chemical fume hood. Do not breathe vapors.

Hazards Identification
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
【Inhalation】May cause respiratory tract irritation. May cause irritation of the mucous membranes.
【Skin】May cause skin irritation.
【Eyes】Causes mild eye irritation.
【Hazards】When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
【EC Risk Phrase】R 36/37/38 40
【EC Safety Phrase】S 26 36/37/39
【UN (DOT)】2810

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Poison Class】3

Fire Fighting Measures
【Flash Point】157℃
【Autoignition】500℃
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
【Fire Potential】Combustible material: may burn but does not ignite ily.

Accidental Release Measures
【Small spills/leaks】Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.

Stability and Reactivity
【Disposal Code】3
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong bases, strong oxidizing agents.
【Decomposition】Hydrogen chloride, carbon monoxide, oxides of sulfur, carbon dioxide, chloride fumes.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.

Transport Information
【UN Number】2810
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2904 10 00