Product Identification
【Product Name】3-Nitrobenzonitrile ；间硝基苯腈
【Synonyms】1-Cyano-3-nitrobenzene
【CAS】619-24-9
【Formula】C7H4N2O2
【Molecular Weight】148.12
【EINECS】210-587-7
【RTECS】DI4900000
【RTECS Class】Agricultural Chemical and Pesticide; Mutagen
【Beilstein/Gmelin】637674
【Beilstein Reference】4-09-00-01067
Physical and Chemical Properties
【Appearance】Light yellow powder.
【Solubility in water】Insoluble
【Melting Point】110℃
【Boiling Point】258℃
【Vapor Pressure】0.01 (25℃)
【Partition Coefficient】1.17
【Heat Of Vaporization】49.6 kJ/mol
First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation. Use only in a chemical fume hood.
Hazards Identification
【Inhalation】Causes respiratory tract irritation. Can produce delayed pulmonary edema. May be metabolized to cyanide which in turns act by inhibiting cytochrome oxidase impairing cellular respiration.
【Skin】Causes skin irritation.
【Eyes】Causes eye irritation. May cause chemical conjunctivitis.
【Ingestion】May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Metabolism may release cyanide, which may result in headache, dizziness, weakness, collapse, unconsciousness and possible death.
【EC Risk Phrase】R 20/21/22
【EC Safety Phrase】S 22 36/37
【UN (DOT)】3276
Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration. Effects may be delayed.
【Poison Class】2
Fire Fighting Measures
【Flash Point】110
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
【Fire Potential】Non-Combustible
Accidental Release Measures
【Small spills/leaks】Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
【Disposal Code】9
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Incompatibilities】Strong oxidizing agents, strong bases.
【Decomposition】Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
【Combustion Products】Fire may produce irritating, corrosive and/or toxic gases.
Transport Information
【UN Number】3276
【Hazard Class】6.1
【Packing Group】I; II; III
【HS Code】2926 90 95