Product Identification
【Product Name】1-(Aminomethyl)cyclohexaneacetic acid
【Synonyms】Neurontin 加巴喷丁盐酸盐
【CAS】60142-96-3
【Formula】C9H17NO2
【Molecular Weight】171.24
【EINECS】262-076-3
【RTECS】GU6496000
【RTECS Class】Drug
【Merck】12,4343
【Beilstein/Gmelin】2359739
【Beilstein Reference】6-14
Physical and Chemical Properties
【Appearance】Off-white powder.
【Solubility in water】Very soluble
【Melting Point】165 - 152℃
【Boiling Point】314℃
【Vapor Pressure】0.0001 (25℃)
【Density】1.257 g/cm3
【pKa/pKb】4.72 (pKa)
【Heat Of Vaporization】61.1 kJ/mol
【Usage】Anticonvulsant with unknown mechanism of action. Exhibits antinociceptive, anxiolytic, neuroprotective and anti-epileptic effects.
First Aid Measures
【Ingestion】If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
【Inhalation】If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and Storage
【Storage】Keep tightly closed.
Hazards Identification
【Skin】Causes skin irritation. Multiple Routes: May be harmful by inhalation, ingestion, or skin absorption. Vapor or mist is irritating to the eyes, mucous
【Hazards】Emits toxic fumes under fire conditions.
【EC Risk Phrase】61 36/37/38
【EC Safety Phrase】53 22 26 36/37/39 45
Exposure Controls/Personal Protection
【Personal Protection】Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. Wear disposable coveralls and discard them after use.
【Respirators】vernment approved respirator.
【Exposure Effects】Toxic. May cause harm to the unborn child. Irritating to eyes, respiratory system and skin. Target organ(s): Nerves. Pancreas.
Fire Fighting Measures
【Flash Point】144℃
【Fire Fighting】Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release Measures
【Small spills/leaks】Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and Reactivity
【Stability】Stable at normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Carbon monoxide, Carbon dioxide.