Product Identification
【Product Name】Indole-2-carboxylic acid
【Synonyms】2-吲哚甲酸
【CAS】1477-50-5
【Formula】C9H7NO2
【Molecular Weight】161.16
【EINECS】216-030-4
【Beilstein/Gmelin】124132
【Beilstein Reference】5-22-03-00005

Physical and Chemical Properties
【Appearance】Off-white powder.
【Solubility in water】Very soluble
【Melting Point】203-206℃
【pKa/pKb】4.44 (pKa)
【Partition Coefficient】1.19

First Aid Measures
【Ingestion】Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage
【Storage】Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light.

Hazards Identification
【Ingestion】May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
【Inhalation】May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
【Skin】May cause skin irritation.
【Eyes】May cause eye irritation.
【EC Risk Phrase】R 22 36/37/38
【EC Safety Phrase】S 26 36/37/39

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear appropriate protective eyeglasses or chemical safety ggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures
【Small spills/leaks】Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity
【Disposal Code】4
【Stability】Stable under normal temperatures and pressures. Light sensitive.
【Incompatibilities】Strong oxidizing agents.
【Decomposition】Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information
【HS Code】2933 99 90