Product Identification
【Product Name】2-Hydroxy-2-phenylacetophenone
【Synonyms】Benzoylphenyl carbinol ；安息香醇
【CAS】119-53-9
【Formula】C14H12O2
【Molecular Weight】212.25
【EINECS】204-331-3
【RTECS】DI1590000
【RTECS Class】Tumorigen; Mutagen
【Merck】13,1094
【Beilstein/Gmelin】391839
【Beilstein Reference】4-08-00-01279

Physical and Chemical Properties
【Appearance】Slightly acrid taste. When broken the fresh surfaces have a milky-white color.
【Solubility in water】300 mg/L
【Melting Point】130~132℃
【Boiling Point】344℃
【Vapor Pressure】3E-5 (25℃)
【Density】1.31 g/cm3 (20℃)
【pKa/pKb】12.28 (pKa)
【Partition Coefficient】2.45
【Heat Of Vaporization】61.9 kJ/mol
【Usage】In organic syntheses.

First Aid Measures
【Ingestion】DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
【Inhalation】IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
【Skin】IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
【Eyes】First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage
【Storage】Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
【Handling】All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification
【Inhalation】Acute effects - cough, sore throat. Irritates eyes, skin and respiratory tract.
【Skin】Redness
【Eyes】Redness
【EC Safety Phrase】S 22 24/25

Exposure Controls/Personal Protection
【Personal Protection】protective gloves. Safety ggles.
【Respirators】Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
【Exposure Effects】The toxological properties of this substance have not been fully investigated.
【Poison Class】3

Fire Fighting Measures
【Flash Point】155℃
【Autoignition】182℃
【Fire Fighting】Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
【Fire Potential】This material is probably combustible.

Accidental Release Measures
【Small spills/leaks】If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity
【Disposal Code】3
【Stability】No data.
【Incompatibilities】Sensitive to heat and light Incompatible with oxidizers.

Transport Information
【HS Code】2914 40 90